Isolation and Properties of Secretory Granules from Rat Islets of Langerhans

نویسندگان

  • S. L. Howell
  • D. A. Young
  • P. E. Lacy
چکیده

Beta granules isolated from rat islets of Langerhans and subjected only to phosphotungstic acid had, in negatively stained images, a 50-A periodicity. This periodicity was also observed in thin-section profiles of beta granules in intact cells. In shadowed preparations, the granules were spherical in shape and had irregular edges and surface structure. The presence of such a periodicity in the beta granule indicates that its matrix may be composed of a crystalline material.

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عنوان ژورنال:
  • The Journal of Cell Biology

دوره 41  شماره 

صفحات  -

تاریخ انتشار 1969